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Anomaly scan: the complete guide to your baby's 18–22 week anatomy scan

The anomaly scan — also called the TIFFA or Level 2 scan — is the most detailed structural examination of your baby in pregnancy. This guide explains the timing, what is checked, what "soft markers" mean, and what happens if a concern is found.

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Medically reviewed by Dr. Nayana N Sunku DMRD · DNB Radiology · Fetal Medicine Fellow
Published 5 July 2026 · 8 min read

What this article covers

  • Why the 18–22 week window matters
  • Every organ system the scan examines
  • What a "soft marker" finding means
  • How the anomaly scan differs from NT screening
  • What happens if a concern is identified

Quick facts

  • Done between 18 and 22 weeks (FOGSI & ISUOG guidance)
  • Takes 30–45 minutes; a full bladder is usually needed
  • Checks brain, spine, heart, kidneys, limbs and more
  • A normal scan is reassuring but cannot rule out everything
  • Sex determination is not performed, per PCPNDT law

Why the 18–22 week window matters

The anomaly scan is the single most comprehensive structural ultrasound performed during pregnancy. FOGSI and ISUOG guidance places the ideal window at 18 to 22 weeks: before 18 weeks, the baby's organs are often too small to assess in full detail; scanning much later narrows the time available for further evaluation or specialist referral if any finding needs a closer look.

Many centres use a structured scanning protocol that steps through the fetal spine, head, chest, abdomen, pelvis, limbs and face in a fixed sequence, alongside two real-time sweeps to confirm the baby's position, heartbeat, and overall orientation. This systematic approach — rather than a quick freehand look — is what makes the scan reliable.

Only the fetal structures documented in your scan report have been assessed. Details not mentioned in the report — such as finger or toe counts, or the external ears — are not part of a routine anomaly scan.

What the anomaly scan checks

The scan examines the baby's anatomy system by system. A typical examination covers:

Brain & head

Skull shape, brain ventricles, cerebellum, and midline structures

Spine

Full spine checked for alignment and skin covering

Face

Profile, lips and upper jaw, orbits

Heart

Four chambers, outflow tracts, and rhythm

Abdomen

Stomach, bowel, abdominal wall and cord insertion

Kidneys & bladder

Kidney structure and urine-filled bladder

Limbs

All four limbs, long bones and proportions

Placenta & fluid

Placental position and amniotic fluid volume

Growth & wellbeing

Fetal measurements and cervical length screening

A normal, detailed anomaly scan is genuinely reassuring — the large majority of scans show a healthy, normally developing baby. That said, no scan can guarantee the exclusion of every possible condition; it is a highly sensitive screening tool, not an absolute guarantee.

Understanding "soft markers"

Occasionally a report mentions a "soft marker" — a minor finding such as an echogenic bowel, a choroid plexus cyst, a slightly dilated kidney (pyelectasis), or a single umbilical artery. On their own, soft markers are not diagnoses and most babies with an isolated soft marker are entirely healthy.

Depending on the specific marker, your other screening results, and your individual risk factors, your obstetrician may suggest an additional test such as NIPT or a follow-up scan. This is a precautionary step, not a sign that something is definitely wrong.

Anomaly scan vs. NT scan

  • NT scan (11–14 weeks) with double marker blood test screens chromosomal risk early
  • Anomaly scan (18–22 weeks) is a full structural survey, not primarily a chromosomal screen
  • The two together give a much fuller picture than either alone

If a concern is found

  • Your radiologist will explain the finding clearly and without alarm
  • A follow-up scan, fetal medicine consult, or further test may be advised
  • Many findings turn out to be minor variants or resolve on rescan

What to expect at your appointment

  • A full bladder is usually recommended — confirm timing when booking
  • The scan takes 30 to 45 minutes and is done over the abdomen
  • If the baby is in an awkward position, you may be asked to walk around and return
  • Bring previous scan reports and your pregnancy file
  • Under the PCPNDT Act, 1994, sex determination is not performed or disclosed under any circumstances

Common questions

When exactly should the anomaly scan be done?

FOGSI and ISUOG guidance recommends performing the anomaly scan between 18 and 22 weeks. Earlier, structures may be too small to assess reliably; later, the window for further evaluation narrows.

What does the anomaly scan actually check?

It systematically examines the brain, spine, face, heart, stomach, kidneys, bladder, abdominal wall and limbs, along with placenta position and amniotic fluid. Only what's documented in your report was assessed.

What is a soft marker on an anomaly scan?

A minor finding — like an echogenic bowel or choroid plexus cyst — that alone doesn't indicate a problem but may prompt your doctor to suggest additional testing depending on your overall risk profile.

Can the anomaly scan detect Down syndrome?

It can pick up some cases through associated markers, but first trimester combined screening (NT scan with double marker test) or NIPT are considerably more sensitive tools for this specific purpose.

Do I need a full bladder for the anomaly scan?

Yes, it's usually recommended as it helps visualise the lower uterus and pelvic structures more clearly. The scan typically takes 30 to 45 minutes.

What patients say
★★★★★

"I have had all my pregnancy scans with Dr Nayana. She is the most professional, compassionate and amazing. She has all the patience to explain and answer my 100s of questions with a beautiful smile on her face. I highly recommend Nitara for all pregnancy scans."

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Sneh Khathuria
11 months ago · Google
★★★★★

"I went to Dr. Nayana for my pregnancy scans and I really like her. She is very kind and has good knowledge. She never hesitates to answer any questions, even small or silly ones. She explains everything very patiently."

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Prameela B
2 months ago · Google

Anomaly scan in HSR Layout, Bengaluru

Nitara Scans and Diagnostics offers the anomaly scan (TIFFA) and full second-trimester pregnancy imaging in HSR Layout, Bengaluru. Every scan is personally performed by Dr. Nayana N Sunku — DMRD, DNB Radiology, Fetal Medicine Fellow — with time for a clear explanation after the scan.

Medical disclaimer: This article is for patient education purposes only and does not constitute medical advice. Please consult a qualified obstetrician or radiologist for an assessment of your individual pregnancy.
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